Preimplantation Genetic Screening (PGS or PGD-A)

Preimplantation Genetic Screening (PGS or PGD-A)

PGT stands for Preimplantation Genetic Testing. It is a type of genetic testing that is performed on embryos created through in vitro fertilization (IVF) before they are implanted in the uterus. The purpose of PGT is to identify embryos that have genetic disorders or chromosomal abnormalities, which can increase the risk of pregnancy loss or the birth of a child with a genetic condition.

There are several types of PGT, including:

  1. PGT-A (also known as aneuploidy screening): Tests for the number of chromosomes in the embryo, which can help detect chromosomal abnormalities.
  2. PGT-M (also known as monogenic testing): Tests for specific genetic disorders that are caused by mutations in a single gene.
  3. PGT-SR (also known as structural rearrangement testing): Tests for structural changes in the chromosomes that can cause genetic disorders.

PGT can increase the chances of a successful pregnancy by selecting the most viable embryos for transfer. It can also help reduce the risk of miscarriage and increase the chances of having a healthy baby. However, it’s important to consider the ethical and emotional implications of PGT and to discuss the options and potential outcomes with a doctor or genetic counselor before making a decision.

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